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Anti-RANK 抗體 [9A725] (Phycoerythrin) (ab45092)產品信息：
- Product name:Anti-RANK antibody [9A725] (Phycoerythrin)...
- Description
Mouse monoclonal [9A725] to RANK (Phycoerythrin)
- ConjugationPhycoerythrin. Ex: 488nm, Em: 575nm
- Tested applicationsFlow Cyt
- Species reactivity
Reacts with: Mouse, Human
- Immunogen
A fusion protein containing amino acid residues 326-616 of human RANK.
- EpitopeThis antibody recognizes an epitope located between amino acid residues 330-427 of human RANK.
- Positive control
- RAW cells
Properties
- FormLiquid
- Storage instructionsStore at +4°C.
- Storage bufferPreservative: 0.05% Sodium Azide
Constituents: PBS Concentration 50 µg at 0.5 mg/ml
- PurityProtein G purified
- Clonality Monoclonal
- Clone number9A725
- IsotypeIgG1
- Light chain typekappa
- Research Areas
- Immunology
- Innate Immunity
- Cytokines
- TNF Superfamily
- Signal Transduction
- Adapters
- Transmembrane
- Signal Transduction
- Growth Factors/Hormones
- TNF
- Signal Transduction
- Cytoskeleton / ECM
- Extracellular Matrix
- Structures
- Bone
- Cardiovascular
- Atherosclerosis
- Vascular Inflammation
- Inflammatory mediators
Applications
Our Abpromise guarantee covers the use of ab45092 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Notes |
|---|---|
| Flow Cyt | Flow Cyt: Use 0.5-2µg for 106 cells. (intracellular). |
Target
- FunctionReceptor for TNFSF11/RANKL/TRANCE/OPGL; essential for RANKL-mediated osteoclastogenesis. Involved in the regulation of interactions between T-cells and dendritic cells.
- Tissue specificityUbiquitous expression with high levels in skeletal muscle, thymus, liver, colon, small intestine and adrenal gland.
- Involvement in diseaseDefects in TNFRSF11A are the cause of familial expansile osteolysis (FEO) [MIM:174810]. FEO is a rare autosomal dominant bone disorder characterized by focal areas of increased bone remodeling. The osteolytic lesions develop usually in the long bones during early adulthood. FEO is often associated with early onset deafness and loss of dentition.
Defects in TNFRSF11A are a cause of Paget disease of bone type 2 (PDB2) [MIM:602080]; also known as familial Paget disease of bone. PDB2 is a bone-remodeling disorder with clinical similarities to FEO. Unlike FEO, however, affected individuals have involvement of the axial skeleton with lesions in the spine, pelvis and skull.
Defects in TNFRSF11A are the cause of osteopetrosis autosomal recessive type 7 (OPTB7) [MIM:612301]; also called osteoclast-poor osteopetrosis with hypogammaglobulinemia. Osteopetrosis is a rare genetic disease characterized by abnormally dense bone, due to defective resorption of immature bone. The disorder occurs in two forms: a severe autosomal recessive form occurring in utero, infancy, or childhood, and a benign autosomal dominant form occurring in adolescence or adulthood. OPTB7 is characterized by paucity of osteoclasts, suggesting a molecular defect in osteoclast development. OPTB7 is associated with hypogammaglobulinemia. - Sequence similaritiesContains 4 TNFR-Cys repeats.
- Cellular localizationMembrane.
- Information by UniProt
Database links
- Entrez Gene: 8792 Human
- Entrez Gene: 21934 Mouse
- Omim: 603499 Human
- SwissProt: Q9Y6Q6 Human
- SwissProt: O35305 Mouse
- Unigene: 204044 Human
- Unigene: 6251 Mouse
Alternative names
- Activator of NFKB antibody
- Activator of NFKB antibody
- CD 265 antibody
Anti-RANK antibody [9A725] (Phycoerythrin) images
![Flow Cytometry - RANK antibody [9A725] (Phycoerythrin) (ab45092)](http://www.abcam.cn/ps/datasheet/images/45/ab45092/RANK-Primary-antibodies-ab45092-1.jpg)
Flow Cytometry - RANK antibody [9A725] (Phycoerythrin) (ab45092)
Intracellular flow analysis of RANK in RAW cells using 0.5 µg of ab45092. Green histogram represents isotype control; red represents ab45092.
公司介紹：
Abcam位于英國的劍橋科學園，成立于1998年，專門生產和分銷研究型抗體。主要創立人Jonathan Milner和實驗室同事構思成立一間了解科研人員需要的網上抗體公司，理念是Abcam銷售質量高的抗體，并提供zui全面、誠實、時新的說明書，快速的送貨服務，及高效率的顧客和服務。我們的在線目錄(www.414168.com) 已有差不多100,000種抗體和試劑，并不斷添加，供應予百多個國家。Abcam于2005年11月在倫敦證券交易所上市，在美國馬薩諸塞州、日本東京及香港均設有分公司。
Abcam 一直致力加強產品線，為使研究員更容易找到蛋白質研究試劑產品，在2011并購了美國的MitoSciences公司，加強了免疫分析方面的產品供應；同年也并購了英國的Ascent Scientific 公司，開展了生化試劑的供應。在2012年，Abcam并購了美國的Epitomics 公司，成為一家有的RabMAbs® 供應商。
Abcam 的 目標是給世界上的抗體建立zui大的在線目錄，為各地科學家提供*產品，成為各國科學界的重要伙伴。我們為所有產品提供來使客戶獲得預期的結 果。為提供高質量的抗體來指向盡可能多的靶蛋白，我們盡所能在盡可能多的應用和物種中檢測每種抗體。我們相信誠信才是上策，在我們的上會發布有關我們 每一種產品的盡可能多的信息。
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Abcam ab1262Mouse monoclonal [GA90] to CD45500ul3996CD45hystemcell一抗
Abcam ab12623Rabbit polyclonal to IL3 （Biotin）25ug3996IL-3hystemcell一抗
Abcam ab1263Goat polyclonal to Myc tag （FITC）100ug3996Myc taghystemcell一抗
Abcam ab12631HIF Prolyl Hydroxylases panel1kit7049HIF Prolyl Hydroxylases panel試劑盒及其他產品試劑盒
Abcam ab1264Mouse IgG1 （HybIgG1） （FITC） - Isotype control1ml3996Mouse IgG1hystemcell同型對照
Abcam ab1265Goat polyclonal to HA tag （HRP）100ug3996HA taghystemcell一抗
Abcam ab12650Rabbit polyclonal to IL16 （Biotin）25ug3996IL-16hystemcell一抗
Abcam ab12656Rabbit polyclonal to IP10 （Biotin）25ug3996IP10hystemcell一抗
Abcam ab1266Goat polyclonal to HA tag （FITC）250ug3996HA taghystemcell一抗
Abcam ab1267Goat polyclonal to Glu-Glu tag （HRP）100ug3996Glu-Glu taghystemcell一抗
Abcam ab12675Rabbit polyclonal to GPCR MCH250ug3996GPCR MCH2hystemcell一抗
Abcam ab12678Rabbit polyclonal to GPR 17950ug4940GPCR AGR9hystemcell一抗
Abcam ab1268Goat polyclonal to Glu-Glu tag （FITC）250ug3996Glu-Glu taghystemcell一抗
Abcam ab12680Rabbit polyclonal to D650ug3996GPCR D6hystemcell一抗
Abcam ab12209Mouse monoclonal [mAbcam 12209] to Histone H3 （tri methyl K4） - ChIP Grade100ug3885Histone H3hystemcell一抗
Abcam ab1221Rabbit polyclonal to Ovalbumin1mg4418Ovalbuminhystemcell一抗
Abcam ab12210Mouse monoclonal [AZ27] to PLK1100ug3996Polo like kinasehystemcell一抗
Abcam ab12211Mouse monoclonal [AZ34] to PLK1100ug3996Polo like kinasehystemcell一抗
Abcam ab12212Mouse monoclonal [AZ44] to PLK1100ug3996Polo like kinasehystemcell一抗
Abcam ab12213Goat polyclonal to c-Myc （HRP）50ug3996c-Mychystemcell一抗
Abcam ab12214Mouse monoclonal to Treponema pallidum100ug3996Treponema pallidumhystemcell一抗
Abcam ab12217Mouse monoclonal [CSL1-5] to Calpastatin50ug3996Calpastatinhystemcell一抗
Abcam ab12219Mouse monoclonal [BU6-4] to BrdU50ug3996BrdUhystemcell一抗
Abcam ab1222Rabbit polyclonal to Superoxide Dismutase 1100ul3996SOD,Superoxide Dismutasehystemcell一抗
Abcam ab1222Rabbit polyclonal to Superoxide Dismutase 11ml3996SOD,Superoxide Dismutasehystemcell一抗
Abcam ab12220Mouse monoclonal [GTS-1] to Heme Oxygenase 150ug3996HO-1,Heme Oxygenase 1hystemcell一抗
Abcam ab12221Rabbit polyclonal to N Cadherin100ug4418N Cadherinhystemcell一抗
Abcam ab12222Mouse monoclonal [NCC-CAD-299] to P cadherin50ug3996P cadherinhystemcell一抗
Abcam ab12223Mouse monoclonal [10C3] to KDEL - ER Marker100ug4418KDELhystemcell一抗
Abcam ab12228Mouse monoclonal [UC1MT] to Metallothionein100ug4418Metallothioneinhystemcell一抗
Abcam ab1223Rabbit polyclonal to Transferrin10mg4218Transferrinhystemcell一抗
Abcam ab12231Mouse monoclonal [3] to Amphiphysin50ug3996Amphiphysinhystemcell一抗
Abcam ab12233Rabbit polyclonal to Calcineurin A50ug3996Calcineurin Ahystemcell一抗
Abcam ab12234Rabbit polyclonal to Rabphilin 3A50ug3996Rabphilin 3Ahystemcell一抗
Abcam ab12239Rabbit polyclonal to Synapsin I50ug3996Synapsin Ihystemcell一抗
Abcam ab1224Rabbit polyclonal to Cyclin D1100ul4285Cyclin D1hystemcell一抗
Abcam ab12241Rabbit polyclonal to Chromogranin C100ul3996Secretogranin IIhystemcell一抗
Abcam ab12242Rabbit polyclonal to Chromogranin B100ul3996Chromogranin Bhystemcell一抗
Abcam ab12243Chicken polyclonal to Raspberry Bushy Dwarf Virus Coat Protein125ug3996Raspberry Bushy Dwarf Virus Coat Proteinhystemcell一抗
Abcam ab12244Chicken polyclonal to Tomato Spotted Wilt Virus Core Protein125ug3996Tomato Spotted Wilt Virus Core Proteinhystemcell一抗
Abcam ab12246Mouse monoclonal to Staphylococcus Enterotoxin A100ug3996Enterotoxin Ahystemcell一抗
Abcam ab12249Rabbit polyclonal to TRPC650ul4274TRPC6hystemcell一抗
Abcam ab1225Mouse monoclonal [BB12+CB19] to CD3+CD19 （Dual color: FITC+PE）500ul3996CD3/CD19hystemcell一抗
Abcam ab12251Mouse monoclonal to Beta Lactamase500ug3996Beta Lactamasehystemcell一抗
Abcam ab12252Mouse monoclonal to Beta Lactamase500ug3996Beta Lactamasehystemcell一抗
Abcam ab12253Rabbit polyclonal to Respiratory Syncytial Virus 50ug3996RSVhystemcell一抗
Abcam ab12254Mouse monoclonal [AS61] to EDG325ug3996EDG3hystemcell一抗
Abcam ab1226Mouse monoclonal [BB12+LN3] to CD3+HLA Class II （Dual color: FITC+PE）500ul3996CD3/HLA-DRhystemcell一抗
Abcam ab12261Rabbit polyclonal to Nurr1100ug3996Nurr1hystemcell一抗
Abcam ab12261Rabbit polyclonal to Nurr1100ug3996Nurr1hystemcell一抗
Abcam ab12265Rabbit polyclonal to beta Amyloid 1-40100ul3996beta Amyloid 1-40hystemcell一抗
Abcam ab12266Mouse monoclonal [DE2B4] to Amyloid Precursor Protein1ml3996Amyloid Precursor Protein,APPhystemcell一抗
Abcam ab12267Rabbit polyclonal to beta Amyloid 1-42100ul3996beta Amyloid 1-42hystemcell一抗
Abcam ab12268Rabbit polyclonal to Amyloid beta precursor protein100ul3996Amyloid beta precursor protein,APPhystemcell一抗
Abcam ab12269Rabbit polyclonal to Amyloid beta precursor protein100ul3996Amyloid beta precursor protein,APPhystemcell一抗
Abcam ab1227Rabbit polyclonal to Biotin100ug3996Biotinhystemcell一抗
Abcam ab12270Rabbit polyclonal to Amyloid beta precursor protein100ul3996Amyloid beta precursor protein,APPhystemcell一抗
Abcam ab12271Rabbit polyclonal to Amyloid beta precursor protein100ul3996Amyloid beta precursor protein,APPhystemcell一抗
Abcam ab12272Rabbit polyclonal to Presenilin 1100ul3996Presenilin 1hystemcell一抗
Abcam ab12273Rabbit polyclonal to Presenilin 1100ul3996Presenilin 1hystemcell一抗
Abcam ab12274Rabbit polyclonal to GAP43 - Neuronal Marker100ul3996GAP43hystemcell一抗
Abcam ab12275Rabbit polyclonal to Proprotein Convertase 2100ul3996Prohormone Convertase 2hystemcell一抗
Abcam ab12277Rabbit polyclonal to Mannosidase II - Golgi Marker100ul3996Mannosidase IIhystemcell一抗
Abcam ab1228Sheep polyclonal to Biotin100ug3996Biotinhystemcell一抗
Abcam ab12281Rabbit polyclonal to Cdc27 （phospho T244）100ug3996Cdc27hystemcell一抗
Abcam ab12282Rabbit polyclonal to Apc6 （phospho T580）100ug3996Apc6hystemcell一抗
Abcam ab12286Rabbit polyclonal to Drosha100ug3996Droshahystemcell一抗
Abcam ab12289Rabbit polyclonal to HIF1AN 100ug3885FIH/asparagine hydroxylasehystemcell一抗
Abcam ab1229Goat polyclonal to V5 tag （Agarose）100ug3996V5 taghystemcell一抗
Abcam ab12290Rabbit polyclonal to UBE2C100ug3996UBE2Chystemcell一抗
Abcam ab12292Rabbit polyclonal to Cdc4/Fbw7/hSel 10100ug3996Cdc4/Fbw7/hSel 1hystemcell一抗
Abcam ab12295Mouse monoclonal [25D5 ] to PSMC5100ug3996SUG1hystemcell一抗
Abcam ab12296Rabbit polyclonal to B MyB200ul3996B MyBhystemcell一抗
Abcam ab12297Rabbit polyclonal to p95 NBS1 （phospho S432）100ug3996p95 NBS1hystemcell一抗
Abcam ab123Rabbit polyclonal to EMSY50ul3996EMSYhystemcell一抗
Abcam ab1230Goat polyclonal to T7 tag® （Agarose）100ug3996T7 taghystemcell一抗
Abcam ab12300Rabbit polyclonal to Emi1200ul2664Emi1hystemcell一抗
Abcam ab12300Rabbit polyclonal to Emi1200ul2664Emi1hystemcell一抗
Abcam ab12301Nurr1 peptide100ug2010Nurr1蛋白/多肽多肽
Abcam ab12306HIF1AN peptide100ug2010HIF1AN 蛋白/多肽多肽
Abcam ab12307Drosha peptide100ug2010Drosha蛋白/多肽多肽
Abcam ab1231Goat polyclonal to 6X His tag® （Agarose）100ug3996His Taghystemcell一抗
Abcam ab12310B MyB peptide100ug2010B MyB蛋白/多肽多肽
Abcam ab12311Cdc4/Fbw7/hSel 10 peptide100ug2010Cdc4/Fbw7/hSel 10蛋白/多肽多肽
Abcam ab12314Emi1 peptide100ug2010Emi1蛋白/多肽多肽
Abcam ab12317Rabbit polyclonal to KMT1E/SETDB1 - ChIP Grade50ug3996SETDB1hystemcell一抗
Abcam ab12318Rabbit polyclonal [BL893] to Topoisomerase II alpha50ug3996Topoisomerase II alphahystemcell一抗
Abcam ab12319Rabbit polyclonal to DIAPH250ug3996DIAPH2hystemcell一抗
Abcam ab1232Mouse monoclonal [EDU-2+733] to CD4+CD8 （Dual color: FITC+PE）500ul3996CD4/CD8hystemcell一抗
Abcam ab12320Rabbit polyclonal to RPA7050ug3996RPA70hystemcell一抗
Abcam ab12321Rabbit polyclonal to COPS350ug3996COPS3hystemcell一抗
Abcam ab12322Rabbit polyclonal [BL1061] to COPS450ug3996COPS4hystemcell一抗
Abcam ab12323Rabbit polyclonal to JAB150ug3996JAB1hystemcell一抗
Abcam ab12324Rabbit polyclonal to Aurora A50ug3996Aurora Ahystemcell一抗
Abcam ab12325Rabbit polyclonal to RBM1450ug3996CoAAhystemcell一抗
Abcam ab12326Rabbit polyclonal to HCC150ug3885HCC1hystemcell一抗
Abcam ab12327Rabbit polyclonal to FHL250ul3996FHL2hystemcell一抗
Abcam ab12328Rabbit polyclonal to FHL250ul3996FHL2hystemcell一抗
Abcam ab12329Rabbit polyclonal to TRIP650ug3996TRIP6hystemcell一抗
Abcam ab1233Goat polyclonal to HA tag （Agarose）100ug3996HA taghystemcell一抗
Abcam ab12330Rabbit polyclonal to TRIP650ul3996TRIP6hystemcell一抗
Abcam ab12331Rabbit polyclonal to JLP100ul3996JLPhystemcell一抗
Abcam ab12332Rabbit polyclonal to JLP100ul3996JLPhystemcell一抗
Abcam ab12336Mouse monoclonal [8D1] to Farnesylated and Endoproteolyzed Lamin B1100ug3996Farnesylated and Endoproteolyzed Lamin B1hystemcell一抗
Abcam ab12337Rabbit polyclonal to PIWIL1100ug3885Hiwi/Miwihystemcell一抗
Abcam ab1234Goat polyclonal to Glu-Glu tag （Agarose）100ug3996Glu-Glu taghystemcell一抗
Abcam ab12340Mouse monoclonal [YC10] to GFAP （phospho T7）25ug3996GFAPhystemcell一抗
Abcam ab12341Mouse monoclonal [4E1] to 14-3-3 beta50ug399614-3-3 betahystemcell一抗
Abcam ab12342Mouse monoclonal [AP20] to MAP2 - Neuronal Marker125ug3996MAP2hystemcell一抗
Abcam ab12347Mouse monoclonal [22-IID8B] to 14-3-3 beta+zeta50ug399614-3-3 beta/zetahystemcell一抗
Abcam ab1235Mouse monoclonal [CRIS1+CB19] to CD5+CD19 （Dual color: FITC+PE）500ul3996CD5/CD19hystemcell一抗
Abcam ab12350Mouse monoclonal [M2F6] to Drebrin50ug4418Drebrinhystemcell一抗
Abcam ab12351Rabbit polyclonal to Hsp27100ug3996Hsp25hystemcell一抗
Abcam ab12356Mouse monoclonal [TAU 2] to Tau25ug3996Tauhystemcell一抗
Abcam ab12357Mouse monoclonal [ TAU 2] to Tau （Biotin）25ug3996Tauhystemcell一抗
Abcam ab1236Mouse monoclonal [733+LN3] to CD8+HLA Class II （Dual color: FITC+PE）500ul3996CD8/HLA-DRhystemcell一抗
Abcam ab12362Mouse monoclonal [AGR 131] to Agrin100ug3996Agrinhystemcell一抗
Abcam ab12364Mouse monoclonal [Agr 247] to Agrin100ug3996Agrinhystemcell一抗
Abcam ab12368Mouse monoclonal [9G7-3] to NSF50ug3996NSFhystemcell一抗
Abcam ab12369Rabbit polyclonal to Syntaxin 250ug3996Syntaxin 2hystemcell一抗
Abcam ab1237Mouse monoclonal [FR4D11/F3+CB19] to CD10+CD19 （Dual color: FITC+PE）500ul3996CD10/CD19hystemcell一抗
Abcam ab12370Mouse monoclonal [3D10] to Syntaxin 6100ug3996Syntaxin 6hystemcell一抗
Abcam ab1238Goat polyclonal to DDDDK tag （HRP）200ug3996DDDDK taghystemcell一抗
Abcam ab12380CPEB3 peptide100ug3286CPEB3蛋白/多肽多肽
Abcam ab12385Rabbit polyclonal to BDNF （Biotin）25ug3996BDNFhystemcell一抗
Abcam ab12389SUZ12 peptide100ug2010SUZ12蛋白/多肽多肽
Abcam ab1239Mouse monoclonal [FS02+733] to CD38+CD8 （Dual color: FITC+PE）500ul3996CD38/CD8hystemcell一抗
Abcam ab12392PSD93 peptide100ug2010PSD93蛋白/多肽多肽
Abcam ab12394APH1a peptide100ug2010APH1a蛋白/多肽多肽
Abcam ab12397Pin1 peptide100ug2010Pin1蛋白/多肽多肽
Abcam ab12399Glutamate Receptor 1 （AMPA subtype） peptide - phospho T840100ug2010Glutamate Receptor 1 （AMPA subtype）蛋白/多肽多肽
Abcam ab1240Goat polyclonal to DDDDK tag （Agarose）100ug3996DDDDK taghystemcell一抗
Abcam ab12400Rabbit polyclonal to STAT650ug3996STAT6hystemcell一抗
Abcam ab12401Rabbit polyclonal to STAT650ul3996STAT6hystemcell一抗
Abcam ab12402p40 peptide100ug2010p40蛋白/多肽多肽
Abcam ab12403Rabbit polyclonal to STAT6 （phospho Y641）25ul3996STAT6hystemcell一抗
Abcam ab12404Twilight peptide100ug2010Twilight蛋白/多肽多肽
Abcam ab12405Mouse monoclonal [44.1] to KMT1A/SUV39H1 - ChIP Grade50ul3885SUV39H1hystemcell一抗
Abcam ab12407Mouse monoclonal [Mab1] to Topoisomerase I50ul3996Topoisomerase Ihystemcell一抗
Abcam ab12408Geminin peptide100ug2010Geminin蛋白/多肽多肽
Abcam ab12409Rabbit polyclonal to PPAR gamma 2 50ul3996PPAR gamma 2hystemcell一抗
Abcam ab1241Mouse monoclonal [L1C1+CB19] to Kappa+CD19 （Dual color: FITC+PE）500ul3996Kappa/CD19hystemcell一抗
Abcam ab12411YB1 peptide100ug2010YB1蛋白/多肽多肽
Abcam ab12414Rabbit polyclonal to cAMP100tests3996cAMPhystemcell一抗
Abcam ab12416Rabbit polyclonal to cGMP100tests3996cGMPhystemcell一抗
Abcam ab12417SAP102 peptide100ug2010SAP102蛋白/多肽多肽
Abcam ab12419PSD95 peptide100ug2010PSD95蛋白/多肽多肽
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